Change: the 6 letter f-word.

CHANGE

Noun
* to make the form, nature, content, future course, etc., of (something) different from what it is or from what it would be if left alone: to change one's name; to change one's opinion; to change the course of history.
* to transform or convert
* to substitute another or others for; exchange for something else, usually of the same kind
* to give and take reciprocally; interchange
* to transfer from one (conveyance) to another
* a variation or deviation: a change in the daily routine.
* the supplanting of one thing by another.

Verb
* to become different
* to become altered or modified
* to become transformed or converted
* to pass gradually into
* to make a change or an exchange


Synonyms: about-face*, addition, adjustment, advance, break, compression, contraction, conversion, correction, development, difference, distortion, diversification, diversity, enlargement, innovation, metamorphosis, modification, modulation, mutation, novelty, permutation, reconstruction, refinement, remodeling, reversal, revision, revolution, shift, surrogate, switch, tempering, transformation, transition, transmutation, turn, turnover, variance, variation, variety, vicissitude, accommodate, adapt, adjust, alter, alternate, commute, convert, diminish, diverge, diversify, evolve, fluctuate, make innovations, make over, merge, metamorphose, moderate, modify, modulate, mutate, naturalize, recondition, redo, reduce, reform, regenerate, remake, remodel, renovate, reorganize, replace, resolve, restyle, revolutionize, shape, shift, substitute, tamper with, temper, transfigure, transform, translate, transmute, transpose, turn, vacillate, vary, veer, warp

In other words:

My co-worker has moved to a different area of the building. My boss is about to be replaced (he was interim). The world has shifted on its axis and I don't like it. Not one effing bit.